Obesity currently affects about 78.6 million people in the United States, which accounts for over a third of the total population, and has serious implications on public health. Due to the increasing burden of the disease, research on obesity in crucial to effectively addressing it in the long term. There are a series of medically supervised weight loss methods, including behavioral changes, pre-packed meals, pharmacotherapy and bariatric surgery that can help patients reach a healthy weight and avoid other diseases like diabetes, heart disease, high blood pressure or sleep apnea.

The most appropriate method of treatment for weight loss is a question to be discussed by both physicians and patients. Even when alternative methods are used, diet and exercise are crucial to treat the disease. Below is an overview about the therapies, devices and drugs approved by the U.S. Food and Drug Administration (FDA) for obese patients, as well as the ones being currently studied that can influence the present panorama.

FDA-Approved Weight Loss Medications

  • Adipex-P (Phentermine)
  • Adipost (Phendimetrazine)
  • Alli (Orlistat)
  • Anorex-SR (Phendimetrazine)
  • Appecon (Phendimetrazine)
  • Belviq (Lorcaserin)
  • Bontril PDM (Phendimetrazine)
  • Bontril Slow Release (Phendimetrazine)
  • Contrave (Naltrexone/Bupropion)
  • Desoxyn (Methamphetamine)
  • Didrex (Benzphetamine)
  • Equaline Acid Reducer (Cimetidine)
  • Evekeo (Amphetamine)
  • Fastin (Phentermine)
  • HCG (Chorionic Gonadotropin)
  • Ionamin (Phentermine)
  • Melfiat (Phendimetrazine)
  • Obenix (Phentermine)
  • Obezine (Phendimetrazine)
  • Oby-Cap (Phentermine)
  • Phendiet (Phendimetrazine)
  • Phentercot (Phentermine)
  • Plegine (Phendimetrazine)
  • Pregnyl (Chorionic Gonadotropin)
  • Prelu-2 (Phendimetrazine)
  • Pro-Fast SA (Phentermine)
  • Qsymia (Phentermine/Topiramate)
  • Saxenda (Liraglutide)
  • Statobex (Phendimetrazine)
  • Suprenza (Phentermine)
  • T-Diet (Phentermine)
  • Tagamet (Cimetidine)
  • Tenuate (Diethylpropion)
  • Tepanil (Diethylpropion)
  • Teramine (Phentermine)
  • Topamax (Topiramate)
  • Topiragen (Topiramate)
  • Xenical (Orlistat)
  • Zantryl (Phentermine)

FDA-Approved Weight Loss Medical Devices

  • Lap-Band Gastric Banding System
  • Realize Gastric Band
  • Maestro Rechargeable System

Investigational Weight Loss Therapies

  • Holbaek-method of treatment
  • Laser therapy
  • Massage therapy
  • Deep Brain Stimulation treatment
  • Endocannabinoid-targeted therapy
  • Dexmedetomidine drug
  • Telmisartan and Amlodipine medication
  • fMRI and Ghlrein medication
  • Lamotrigine for binge eating associated to obesity
  • Portable Body Scanner to diagnose obesity
  • Portable Monitoring Device to diagnose sleep apnea in obese patients

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